Product description

【冰球突破官方平台】 The main ingredient of this product is roxithromycin。
Chemical name :9-[0-(2-methoxyethoxy) -methyl] oxime] erythromycin
Chemical structure formula:

【冰球突破mg平台】 The content of this product is white or white powder and particles。
This product is suitable for pharyngitis and tonsillitis caused by streptococcus pyogenes，Sinusitis caused by sensitive bacteria,Otitis media, acute bronchitis, chronic bronchitis acute attack，Pneumonia from mycoplasma pneumoniae or chlamydia pneumoniae;Urethritis and cervicitis caused by chlamydia trachomatis;Skin and soft tissue infection caused by sensitive bacteria。
【冰球突破官方平台】150mg
[Usage and dosage] Oral fasting, the general course of treatment is 5~12 days。Adult: 0 at a time.15g, 2 bites;Can also be 0 at a time.3g, once a day。Children: Weight 2 at a time.5~5mg/kg, twice a day。
Or as prescribed by a doctor。
[Adverse reactions] The main adverse reactions were abdominal pain, diarrhea, nausea, vomiting and other gastrointestinal reactions, but the incidence was significantly lower than erythromycin。Occasionally, skin rash, itching, dizziness, headache, abnormal liver function (elevated ALT and AST), peripheral blood cell decline, etc。
【冰球突破mg平台】 This product should not be used by people who are allergic to any ingredient, erythromycin or other macrolides。
【冰球突破官方平台】
1.Use with caution in patients with liver dysfunction。In severe cirrhosis, the elimination half-life (t1/28) is extended to more than 2 times the normal level, and if it is really needed, a single dose of 0.15g, once a day。
2.Dose adjustment is not required for mild renal insufficiency, and the administration time is doubled for severe renal insufficiency (one dose 0.15g, once a day)
3.There is cross-resistance between this product and erythromycin。
4.In order to obtain a higher blood concentration, this product should be taken with water on an empty stomach (1 hour before or 3 to 4 hours after a meal)。
5.Liver function was tested regularly during medication。
6.If you experience any adverse events and/or adverse reactions during use of this product, please consult your doctor。
7.Please inform your doctor if you are using other drugs。
8.Keep out of reach of children。
[Medication for pregnant and lactating women] Use with caution for pregnant and lactating women。低于0.05% of the dose is discharged into breast milk, and although it has been reported that there is little effect on the baby, it is still necessary to consider whether to discontinue breastfeeding。
[Drug use in children] is not clear。
If there is no significant change in the pharmacokinetics of the elderly, there is no need to adjust the dose。Or as prescribed by a doctor。
【冰球突破官方平台】
1.Not compatible with ergotamine, dihydroergotamine, bromocriptine, terphenadine, ketoconazole and Cisapride。
2.It had little effect on the metabolism of aminophylline, and had no effect on carbamazepine, warfarin, ranitidine and other acid-making drugs。
[Drug overdose] is not clear。
[Pharmacology and toxicology] This product is a semi-synthetic 14-membered macrolide antibiotic。The antibacterial spectrum and antibacterial action are basically similar to erythromycin, the effect on gram-positive bacteria is slightly worse than erythromycin, and the effect on Legionella pneumophila is stronger than erythromycin。The antimicrobial action against Chlamydia pneumoniae, mycoplasma pneumoniae and ureaplasma urealyticum was similar to or slightly stronger than erythromycin。
[Pharmacokinetics] Good oral absorption, high blood peak concentration (Cmax), a single dose of roxithromycin 150mg oral peak concentration (Cmax) about 2 hours after 6.6~7.At 9mg/L, eating reduces bioavailability by about half。Widely distributed, tonsil, sinuses, middle ear, lung, sputum, prostate and other urogenital tract tissue drug concentration can reach the effective treatment level。Its protein binding rate is at blood concentration 2.96% at 5mg/L。Excreted from the body in its original form with 5 metabolites, 7.4% is excreted in urine。The blood elimination half-life (t12) was 8.4-15.5小时。
【冰球突破mg平台】 Dark, sealed, stored in a dry place。
[Packaging] Aluminum plastic packaging, 10 pieces/board X1 board/box。
[Validity] 36 months。
[Executive Standard] China Pharmacopoeia 2015 edition II。
[Approval number] National Drug approval number H20083006